0630 Clinical Symptoms of Our Narcoleptic Patients

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Attention impairments and ADHD symptoms in adult narcoleptic patients with and without hypocretin deficiency

BACKGROUND Attentional complaints are common in narcolepsy patients and can overlap with daytime sleepiness features. Few studies attempted to characterize attentional domains in narcolepsy leading to controversial results. We aimed to assess the impact of hypocretin deficiency on attentional functioning by comparing performances on the attention network test (ANT) of narcoleptic patients with ...

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Elevated Peripheral Visfatin Levels in Narcoleptic Patients

OBJECTIVE Narcolepsy is a severe sleep disorder that is characterized by excessive daytime sleepiness, cataplexies and a tendency towards obesity. Recent discoveries indicate that the major pathophysiology is a loss of hypocretin (orexin) producing neurons due to immunologically mediated degeneration. Visfatin is a recently described proinflammatory adipokine. It is identical to the immune modu...

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Eating disorder and metabolism in narcoleptic patients.

STUDY OBJECTIVE To evaluate eating behavior and energy balance as a cause of increased body mass index (BMI) in narcolepsy. DESIGN Case controlled pilot study. SETTINGS University hospital. PARTICIPANTS 13 patients with narcolepsy (7 "typical" patients, with HLA DQB1*0602 and clear cut cataplexy, with suspected hypocretin deficiency; and 6 "atypical" narcoleptics, i.e., HLA negative or wi...

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Evaluation of Clinical Symptoms in Patients with Different Severities of Carpal Tunnel Syndrome

Background: The carpal tunnel syndrome (CTS) is a common neuropathy caused by the entrapment of the median nerve in the carpal tunnel. It causes pain and paresthesia in the hand. Objectives: To evaluate the role of clinical symptoms of CTS to determine the severity of this disorder. Materials and Methods: This descriptive cross-sectional study examined 75 hands of 40 patients were referred wi...

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Sustained attention assessment of narcoleptic patients: two case reports

Narcolepsy is a sleep disorder characterized by uncontrollable REM sleep attacks which alter the patients wake state and can lead to difficulties in attention aspects, such as maintaining attention when performing activities or tasks. This study aimed to evaluate sustained attention performance of two narcoleptic patients on the d2 Test, Epworth Sleepiness Scale (ESS), Pittsburgh Sleep Quality ...

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ژورنال

عنوان ژورنال: Sleep

سال: 2018

ISSN: 0161-8105,1550-9109

DOI: 10.1093/sleep/zsy061.629